NASAL SUFENTANIL REDUCES HEMODYNAMIC RESPONSE TO DIRECT LARYNGOSCOPY AND TRACHEAL INTUBATION
G.KARACA
1, A.ÖZENSOY
2, TA.AYAZOGLU
2, MA.CANDAN
3, M.ÇALIM
4
BAKIRKÖY DR.SADI KONUK EĞITIM VE ARAŞTIRMA HST 1
KARTAL KOŞUYOLU YÜKSEK IHTISAS EĞITIM VE ARAŞTIRMA HASTANESI 2
RİZE DEVLET HASTANESİ 3
SİVAS DEVLET HST 4
Backgroud:Laryngoscopy and tracheal intubation increase blood pressure
(BP) and heard rate (HR). We studied the effect of sufentanil 0.3 microgr/kg
given intranasal 5 min before surgery on hemodynamic response to direct
laryngoscopy and tracheal intubation
Methods ;
Sixty
patients were randomly allocated to one of the two groups. Group 1 received 2 microgr/kg
of sufentanil and Group 2 received placebo with SF water 5 min before the
induction of anaesthesia. After standart induction technique, study variables,
pulse and noninvasive BP (systolic, diastolic, mean) and HR were noted every
minute for first five minutes then at 10 and 15 minutes. Relevant demographic data
and study variables were recorded
Results:
Mean
systolic BP with sufentanil was lower compared to placebo but it was
significant at 1 min (136+22 vs 149 + 23), 2 min (120+21 vs 136 +24), 10 min
(107 +12 vs 118+16) and 15 min (106 +13 vs 116 413) after intubation
(P<0.005). Mean diastolic BP with sufentanyl was significantly lower at 2
min (91+18 vs 103 + 18), 10 min (79+12 vs 88+13), and 15 min (79 +14 vs 86+12)
after intubation at P<0.005. Decrease in HR with sufentanyl was significant
at 10 min (92 +15 vs 101+18) and 15 min (87+14 vs 99+16) after intubation
(P<0.005)
Conclusıon;
Nasal
sufentanil decreases the response to
laryngoscopy and intubation on
systolic BP at 2 min and 15 min, mean arterial pressure at 2, 10 and 15 min and
HR at 10 and 15 min following laryngoscopy
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